Please check the FAQ section of this link : Download and install Adobe Creative Cloud apps
Although Adobe suggests you install application on the primary drive, it is possible to change the installation destination from the Creative Cloud app preferences. Please note that there will still be shared resources stored on your primary drive. In addition, temporary files will be created on your primary drive during the installation process. The Adobe Creative Cloud desktop app will remain on the default drive.
If you have already installed the app, you need to uninstall it, change the destination drive, reboot the machine and then install the app.
moving to Creative Cloud Download & Install forum