I am unable to install my Lightroom CD on a new computer with Windows 10. Is there a simple guide in plain English? I do not understand computerese.

I don't know how you have configured YOUR computer, but on my computer with Win10 a small box that says (something like) TAP HERE TO SELECT WHAT TO DO pops up on the right side for a few seconds... do you see that when you insert a disc?

OR

Download & Install instructions https://forums.adobe.com/thread/2003339 may help

-includes a way to go to a page to download Adobe programs if you don't have a disc or drive

-Cloud desktop http://helpx.adobe.com/creative-cloud/help/creative-cloud-desktop.html

-Cloud Getting Started https://helpx.adobe.com/creative-cloud.html

-you will need to enter your original serial number during install for non-Cloud programs

-or kglad links in reply #1 here https://forums.adobe.com/thread/2081216 may help

Also go to https://forums.adobe.com/community/creative_cloud/creative_cloud_faq

copy the cd contents to a desktop directory.

double click setup.