"Please close all instances of adobe application manager"

I was in Illustrator happily working away when I hit the save button and it told me there was an error.  I closed out of Illustrator and rebooted my computer.  Now when I click on Apps, it tells me "There's a problem! Please close all instances of adobe application manager to continue."  When I click on the button to Reload Applications, nothing happens.  So, what's up?  I'm on Windows 10.