Hi Jenniporkstain,
Sorry that you are having trouble, please let us know if you get this error while installing Adobe Creative Cloud (CC) apps or Adobe Creative Suite products?
If you are trying to install Adobe Creative Cloud apps on Mac OS Sierra and it fails with an error saying "Installer failed to initialize. This could be due to a missing file." then I would suggest you to try the work around given here: Installing Creative Cloud on macOS 10.12 (Sierra) to resolve the issue.
However, if you are trying to install Creative Suite version of Adobe products then try the steps listed here: Installing Creative Suite on macOS 10.12 (Sierra).
Just in case this doesn't help, then please share a screen shot of the error window. See: FAQ: How do I capture and post a screen shot or video?
Let us know if this helps.