why are Adobe folders popping up all over my Mac?

I got a refurb MacBook Pro about a month ago & installed High Sierra. Installed Adobe Creative Cloud on Feb 18. Since then, Adobe folders have been magically created in several locations, and they have been multiplying into totally random areas:

1. In a /Users/Shared/xxx/xxx/ folder containing some business documents, there is now an Adobe folder with two subfolders: SLCache and SLStore. The SLCache folder is empty; the SLStore folder has an Adobe01.bmp file.
2. Under /Applications/Adobe Bridge 2018 there is an Adobe folder with 4 subfolders: Adobe PCD, AdobeGCClient, SLCache, & SLStore. Seems normal. But there is an identical folder structure under /Users/donna/Music/iTunes/iTunes Music/Donovan. These files are dated March 8, 2018, so they're a fairly new addition.
3. There is another Adobe folder like #2 under Users/donna/Dropbox.
4. At the root of my internal drive there are three folders: /Adobe (with an AdobeGCClient subfolder), /AdobeGCClient (empty), and /SLStore (with Adobe01.bmp). All were created March 1.
5. Several Adobe folders, each containing one OOBE subfolder, have popped up in the weirdest places. One could be normal; it's /Users/Shared/Adobe. But there's one in a WordPress plugin folder in my Sites directory: /Users/donna/Sites/sitename/wp-content/plugins/stream/Adobe, created March 5. Another in a site's root: /Users/donna/Sites/sitename2/Adobe, with files created March 17. And another: /Users/donna/Music/iTunes/iTunes Music/John Mellencamp/Adobe.

I'm downloading a virus scanner. If it doesn't find anything, does anyone have another explanation for this behavior? I couldn't find any reports of it in Google or the forums.

And does someone know which of these are legitimate files that I shouldn't delete?

Thanks for any help!

Donna