Cannot get msi install to work

I’m using DC 15 Classic track downloaded from the LWS site.  I create a mst with the customization wizard and save the transform into the bootstrapper folder.  I can run it successfully using this command at the command line (need command-line since we deploy via Dell Kace):

1. Setup.exe /sALL TRANSFORMS="AcrobatDC_LWS.mst"

With previous versions (XI) we successfully used this string: 

msiexec /i "AcroPro.msi" TRANSFORMS="AcrobatDC_LWS.mst" /qn

It will not work on my Windows 10 test VM only the setup.exe method.   Oddly the msi method works when I test it on real hardware locally.

Any suggestions?  Its not mandatory that we get it to work this way just want to learn more about why it works or doesn’t work and why.

Thanks!