Hi Sam,
Adobe After Effects, Photoshop & Illustrator are resource-intensive applications, requiring more RAM and hard disk space than most other applications. While you can use their files from networks and removable media, you can compromise the performance and reliability of the application.
When you save and open files across a network or from removable media, many variables affect application performance. Consequently, some problems occur more frequently when you work across a network or removable media than when you work from a local hard disk (for example, damaged files, denied access, or slow performance).
For example, Illustrator reads and writes file data while you work on a file. Therefore, the access speed of the disk containing artwork or Illustrator scratch disk files determines how quickly Illustrator can process image data. Internal hard disks have faster access speeds than network servers (that is, a hard disk accessed over a network) or removable media.
For more details please see the following help documents:
https://helpx.adobe.com/photoshop/kb/networks-removable-media-photoshop.html
https://helpx.adobe.com/in/illustrator/kb/illustrator-support-networks-removable-media.html
https://helpx.adobe.com/in/after-effects/using/improve-performance.html
Hope this helps.
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