Glow effect is cropping out on interactive PDF

You are previewing in epub/publish online window, that is NOT a PDF previewer (hence PDF is not in the name if that Preview Window), so what you see in the epub preview has little to do with PDF. Interactive PDF is almost always a very bad idea as it will only work when viewed in Acrobat Reader/Pro (and then some things won't work) and you can not know which app (or even browser) your readers are going to view the PDF.

Instead you can use Publish online and provide your readers the link to your work there.

How are you previewing this? Why did you tag it as Publish Online if it's PDF?

That said, I can't possibly recommend this. Buttons in PDF are notoriously wonky even in Acrobat and beyond that, such as browsers and mobile devices, they don't work at all. 

It depends on how you applied the glow. If you placed your wrapped text as, say, an illustrator element, and you then apply the glow to it using the Direct Selection tool (so that the graphic itself (left image in my example) is selected and not the graphic frame containing it), the glow will be considered part of the graphic, so will be (properly) cropped by the graphic box that contains it. However, if you apply the glow to the whole object (right) using the normal selection tool to select the graphic frame, the glow will go past the edges. Of course, how this works depends entirely on what you have.

You could just always simply expand the sides of the graphic frames so they no longer interfere with the glow.