Is it possible? with a script in a test question numbers automatically assign

Try this,

var myDoc = app.activeDocument, question_no=0;
for(var p=0; p<myDoc.pages.length; p++)
{
    for(var i = myDoc.pages
.textFrames.length-1; i>=0; i--)  
    {  
        question_no++;
        myDoc.pages
.textFrames.texts[0].select();

        app.findGrepPreferences = app.changeGrepPreferences = null;
        app.findGrepPreferences.findWhat = "^\\d+.\\t";
        app.changeGrepPreferences.changeTo  = question_no + ".\t";
        app.selection[0].changeGrep();
        app.findGrepPreferences = app.changeGrepPreferences = null;
    }
    question_no = 1;//If you want continuous page number throughout the document, then hide this line
}  

Vandy