Edit In Photoshop greyed out

When the 'link' between Lightroom Classic and Photoshop has issues, the first step is to try this:

Use the Adobe Creative Cloud Application to uninstall Photoshop. When asked, keep preferences! After this reinstall Photoshop again.

If this doesn't help the nest step is to reinstall both apps Lightroom and Photoshop. Please follow the steps below:

1. Open the Adobe Creative Cloud Desktop Client and uninstall both Photoshop and Lightroom Classic. When asked, keep preferences! 

2. Install Photoshop first and then Lightroom Classic. The right order is very important here!

If this doesn't help try the reinstallation with removing the preferences also.

If this also doesn't help we need more informations about your environment.

Which operating system do you use?

Which version of Lightroom do you use?

Please post the exact version and not only phrases as "recent", "latest" and so on.

Please provide also a copy of your 'System Info'. This can be get from the LrC Help > System Info menu item.

There's a copy button in the System Info dialog. Press this button and paste the info into your next forum post.

Does LrC indicate that the original photo is missing?

https://www.computer-darkroom.com/lr2_find_folder/find-folder.htm

Have you checked the anwsers to any of the numerous similar questions?

... I am not working with origianl picture (btw). ...

By @thomass45764434

Do you work with SmartPreviews? 

Are the original RAW file is accessible when you use the "Edit in Photoshop" function?  If no, make the original file accesible. Photoshop must have access to the original file.