How to delete programs from "Edit In"

To expand on the reply from Ken-

1) Select the Additional External Editor Preset you want to remove from Edit-In.  In the [Preset] disclosure arrow menu.

2025-12-14 07_46_20-Preferences.jpg

2) Click the disclosure arrow menu a second time and choose the 'Delete...' option-

2025-12-14 07_46_32-Preferences.jpg

Alternately-  You can use Windows File Explorer to delete the Preset in the {...\Lightroom\External Editor Presets} folder, and restart Lr-Classic.

C:\Users\{YourName}\AppData\Roaming\Adobe\Lightroom\External Editor Presets

Preferences -> External Editing - You can make changes there.