Print color management issue

Some MACOS users have occasional issues with printing. Oddly, while the Apple does not support customers updating most drivers, GPU drivers for example, they do allow for updating printer drivers, of course this is an external device, so the situation is different.

This is fortunate, as those print drivers go kaput from time to time.

Now this might have nothing to do with your problem, but have you tried reinstalling the printer? That would reinstall a driver.

You should always test output using good color reference images designed for that task. The color reference images RGB values are such that they are set for output and are editing and display agnostic. Test the output this way and examine for the same color issues so we know it's not your image-specific issues causing the problems:
http://www.digitaldog.net/files/2014PrinterTestFileFlat.tif.zip

Start from scratch in LR and create a new user Print Template with every possible setting (for print driver and within LR's module), and try again. When printing with an Epson, always have the driver itself set for Presets: Default Settings, NOT one you created and can use in Photoshop! ALL settings are stored in a template in LR; they all have to be correct, meaning everything you can configure in the print driver outside a saved preset there:

Nobody??