Lightroom / Photoshop Sync error

Hi,

i edited some of my Lightroom files via the Funktion "edit in Photoshop" today. 
Spended 4 Hours of editing of multiple files (parallel) and After finishing i saved the files in photoshop and then closed all files. 
normally All These files would be automaticly reimported as tiff into lightroom. This worked with 3 files.
All other files could Not reimported because Lightroom Systems that i can't Import these edited files. So i opened Photoshop once again and tried to Open the tiffs via "last files". Photoshop now tells that it could Not find These files anymore... wtf

The 3 tiffs that now are back in Lightroom -> the cloudsync wońt work and also the copy of on external ssd is forbidden because lightroom now says that the harddrive is protected against writing files on it. it is Not, this worked for over a year. Nothing has changed. 

Since the Last Update nothing really works Any more... 

Anybody has the Same errors? Somebody has Tipps .