Unable to launch Lightroom

The last properly working version 4.0
In version 4.1 it was no longer possible to export an image with an image logo.
After an update to version 4.2 it is no longer even possible to start lightroom. Lightroom starts up and gives an error report, which I have sent several times. But to date no response from Adobe.
The latest version 4.4 doesn't even allow you to send an error report.
Tried so far: Completely removed everything from Adobe, registry entries and folders.
Rebooted, Creative cloud installed and from there Lightroom 4.4 Same result.
Now use version 4.0 again (latest properly working version)
If I use 4.0, it doesn't give a problem if I do an update then the trouble starts again.
These phenomena also occur on my other PC (about the same configuration) Windows 10 fully up to date.