Brush

My brushes were working just fine for a few hours and now I have tried for several hours to use my brushes in Photoshop and they will not work.  They are photoshops standard bruses.  I closed it and re-open.  I have tried to do a simple hue/saturation adjustment layer and brush white to teeth and it is not working.  Help me if you have any answers.  I use an I Mac and I am in Photoshop 2025.