PSE 22 won't launch after reinstallation

What kind of new install of Win 10 did you perform?  A fresh install after a reformat of a disk, or an install that preserved your prior data?  I assume it was the latter, in which case, there are likely some files that remain that need to be removed. 

While I could probably give you some instructions to remove all traces of Elements from your machine, your best bet is to contact Elements support. You can start a chat session by clicking on the blue Contact Us button under the Help & Support menu at Adobe.com. Or you can contact Support by telephone using the numbers listed here: https://helpx.adobe.com/contact/phone.html.  With your permission, a tech can take control of your computer and fix the problem.