Keyboard shortcuts disappearing - Premiere Pro 24.0 - Mac

I've lost my keyboard shortcuts twice this week after upgrading to 24. They are just gone... all of them. Even things like Cmd+Q to quit the program. No spacebar to play clips... No marking. No copy/paste/cut... nothing. Checking the shortcuts preferences, there are no shortcuts listed on any commands. Resetting preferences has not worked, I've had to delete my user prefs folder and relaunch to get them back. I can't figure out any triggers that are causing this. I was working on a project earlier today for hours. No problems. All shortcuts present and working. Took a break for travel and came back to work tonight (Macbook Pro sleeping). Jumped into Premiere Pro -- all shortcuts gone. I'm stumped.