Media Cache files saving to C drive and not my Cache drive

No matter how many times i state to save in the E drive, the C drive folder keeps filling up. 

 

By @SHOOT FIRST CREATIVE

I notice from the screen dump that the Media Cache Files goes to E:\MEDIA CACHE while Media Cahce Database goes to E:\MEDIA CACHE\

That should not cause the issue, but i would start with to change the Media Cache Database location to E:\MEDIA CACHE instead of E:\MEDIA CACHE\ . If it still behaves the same i would delete the Preferences for Premiere Pro by pressing the Shift-key while launching Premiere Pro. Check the "Reset app preferences" in the dialog that pops up and click Continue.

When you reset the Preferences the Media Cache Files/Media Cache Database will still be set to the folder you choosed since Media Encoder and After Effects share this setting.

Did it make any difference at all?

You only need one post with the same answer. I don't know for sure, as I set all my Project or Production settings to an "S" drive, and then to let the c: drive do some work, I leave the cache settings alone. 

I would try two things. One is take out the space in the "Media Cache" folder name. The second, I would try just directing them to the root of your "E" drive, as I have on my settings in the screenshot.

And is E an internal drive, or external via USB/Thunderbolt?

What size is the E drive, and how much free space is there?