Play Back Troubles

So play back has been something that has been annoying me to no end. No matter what I do I always get dropped frames, even if the footage is 1080p.  I recently upgraded my computer parts. My current build is:

Ryzen Threadripper 2920x (12 Core 3.2ghz)

32GB of Corsair Dominator Platinum 3000hz

EVGA FTW3 1080ti

Corsair 750 Watt Modular Power Supply

Asus Strix x399 MOBO

Most of my footage is either 4k at 24p or 1080p at 120fps.

Even with the specs of my computer I still get dropped frames in playback.

Could it be something todo with my sequence settings or how im editing? Anything info would be appreciated.