Weird playback issues, glitchy screen

Hi there,

The engineering team is currently working on a similar issue. If restarting the system does not help, you can try changing your Renderer (File > Project Settings > General > Set the Renderer to Mercury Playback Engine Software Only). This might affect the playback performance. 

Thanks,

Ishan

Please tag me (@) in your replies so that it notifies me and helps me respond promptly.

Have you installed any new programs, updated Premiere or your OS recently?  Are you running any other programs at the same time?  What peripherals do you have connected besides a mouse and keyboard and hard drive(s).   Try creating a new user account with administrative privileges and sign in to the new account and see if that fixes things...  If you need help doing this, post back...

Also, please use the free MediaInfo and post a screenshot of the properties of your media in tree view:
https://mediaarea.net/en/MediaInfo

Many users are having issues with VFR. If the file is variable frame rate, use Handbrake to convert to constant frame rate before importing into Premiere Pro:
https://handbrake.fr/downloads.php
Here is a tutorial:
https://www.youtube.com/watch?time_continue=34&v=xlvxgVREX-Y

Shutter Encoder may also be used to convert to Constant Frame Rate:
https://www.shutterencoder.com/en/

Delete the Media Cache and Media Cache files:
https://community.adobe.com/t5/premiere-pro/faq-how-to-clear-your-media-cache-in-30-seconds-in-premiere-pro-2020/m-p/11017257/thread-id/260446?page=1

If that doesn't work, try resetting the preferences:
https://community.adobe.com/t5/premiere-pro/faq-how-to-reset-trash-preferences-in-premiere-pro/td-p/8236158?page=1

If that doesn't work, try resetting the Workspaces:
Reset a workspace
Reset the current workspace to return to its original, saved layout of panels.
1. Do one of the following:
• Click the Workspace menu icon and select Reset to Saved Layout.
• Choose Window > Workspace > Reset to Saved Layout.
from here:
https://helpx.adobe.com/premiere-pro/using/workspaces.html

If that doesn't work, try Preferences > Audio Hardware and set Input to None.

If that doesn't work, try creating a new project and import the old one into it.