TOC, search, index links do not work in IE10 after toggling panes

I have RH 10 projects published in WebHelp that have the following behavior in IE10:

1. Click a TOC entry and view the topic as expected.
2. Click other TOC entries and see the corresponding topics.
3. Then click a button on the skin such as Index or Search, then click an entry: the main pane turns white. Even if I just click the Contents button again, none of the entries respond.

This does not happen in Chrome nor in IE10 Compatibilty View, but we don't have the option of using either as a fix.