Hi @pvanstro
Hope you are doing well, and thanks for reaching out.
Microsoft Print to PDF is a MS process and Adobe doesn't have a hold on it.
Please try to create the PDF from the Acrobat ribbon present in the MS Word toolbar and see if that works.
Is this an issue with a particular PDF file or with all the PDFs? Please try with a different PDF file and check. If the file is stored on a shared network/drive please download it to your computer locally and then try again.
What is the version of the Acrobat DC you are using? To check the version go to Help > About Acrobat and make sure you have the recent version 23.06.20320 installed. Go to Help > Check for updates and reboot the computer once.
Also try to repair the installation from the help menu (Win Only) and see if that works.
Please try to reset the Acrobat preferences as described here https://community.adobe.com/t5/acrobat-discussions/how-to-reset-acrobat-preference-settings-to-default/td-p/4792082
You may also try to create a new test user profile with full admin rights in Win or enable the root account in MAC and try using the application there and check.
Let us know how it goes.
~Amal