I cant select a subject in the masks or the sky any more. Just stopped working last week.

I cant select a subject in the masks or the sky any more. Just stoped working last week. Iv done nothing different & every thing is up to dade. Id hate to have to uninstall then reinstall it. Thats a wicked pain in the ass and I bet ill have to reinstall all my brushs too, ahhhh. Any thoughts?