After Effects CS5 on Windows 10

Hello,

I'm having issues on multiple Windows 10 machines running AE CS5.
After install, I can run AE without any issues. Closing and starting again is where the issue occurs. After that, every time I run AE, it starts, some window quickly flashes on the screen and AE just crash, no error message or anything. They only way to run AE again is to reinstall.
I've tried anything I could think of, compatibility mode, deleting all appdata, reseting all settings, fresh Windows 10 machine, versions 10.0.0, 10.0.1, 10.0.2, I even made a snapshots of registry and drive to compare what changes before and after first run to manually revert everything. No success.

Any thoughts?

Thank you kindly,

GZ