Animate/Media Encoder. Pulling my hair out.

I already asked a similar question, but I can't get my head around the responses. So I'm now reverting to this: can someone please PLEASE provide me with an actual workflow for this? The settings I am using are clearly not working. I am using Adobe Animate to produce simple 2D build up animations for a retailer. The file is set up as a portrait 1080p (1080x1920px) canvas. The problem is that looking at the artwork file compared to the finished .mov file after it has been exported as "video/media" and fed through Media Encoder, the difference is night and day. The finished .mov item is unacceptably blurry and the colours aren't as vivid. If I export the Animate file as a "movie", the resulting .swf file is nice and sharp. The format being asked for is a Quicktime .mov with H.264 encoding. So: what preset should I use on export from Animate (currently Format: Quicktime; Preset: H264 Match Source High Bitrate)? As far as Media Encoder presets go, I'm completely in the dark. I haven't used it before as this is the first time I've needed to produce files of this type. It was all going so well up until the file translation bit! ANY help would be greatly appreciated. Thank you in advance.