Using the latest update of Illustrator and I'm using an AMD RX 7800 XT and when I turn overprint preview on I cannot do anything. Zooming, turning colors on and off, does nothing.
We understand that encountering technical issues can be frustrating. Would you mind performing a clean reinstallation of the GPU drivers (Intel / NVIDIA / AMD) and setting the Graphics Preference to High-Performance for Illustrator (https://adobe.ly/3VHkKA4) and checking if it helps?
Also, try running Illustrator under a different administrator account (Windows / macOS) and share your observations.