My RAM gets eaten up by InDesign and Illustrator, up to a usage of 70%

I'd second that suggestion. I actually didn't need the 64GB at work, except when I had to load Fiery Command Workstation for our Xerox servers, which uses an ungodly 5-6GB of ram just by itself. I optimize the system at least twice a week, and have all my files and programs taking up less than 300GB of the drive. By contrast, another system here with the same loadout of files and programs is nearing 90% of its 1TB ssd, because I can't convince my coworker to delete unnecessary files. Windows 10 and 11 are also stupid, because you have to close a program (by default) to free up memory. The following may/may not have an effect on the amount of memory being used, but it actually helped me a bit, and it can greatly increase the longevity of your ssd, especially if it has a low dwpd endurance rating: you can try to disable prefetch/superfetch (sysmain) in Windows, which might lower the amount of data resident in the memory, at the cost of slightly slower initial program access. With a fast cpu and drive combination, this speed loss will not be noticeable. I did it in the registry, but you can also simply turn off the service. I would recommend going through your startup and services lists to disable anything you don't need/want that might be starting automatically and wasting ram. Startup should be safe to edit as is, but be sure you know what you're doing in Services, though, as disabling the wrong service can result in severe malfunctions. I was able to trim over 3GB of wasted ram through this process.