Adobe software temporary files block iCloud Drive

I have had this issue for months, if not years. 

I save almost all my working files in iCloud Drive. This means that, when an Adobe software such as InDesign creates a file, it also creates the backup file in the same folder. 

Almost every day, at the end of the day, I see something like this in my Finder:

Until I restart the Mac or, sometimes, log out-in of macOS, the issue doesn't go away. It is as if some tiniest files got stuck or got lost somewhere in the process. I spent hours and hours with Apple Support and no one has ever been able to fully help me.

Today I finally manage to pinpoint the source of the issue: Adobe temporary files. How can I be so sure? Easy: today I used Adobe software only, nothing else, for the whole day. Illustrator, Animate, InDesign, Acrobat. 

Since moving all my working files outside would be unpractical now, is there a way to tell Adobe softwares to save the temporary backup files somewhere else? 

Thank you