Color profiles - must they all be identical?

Hi @kathleend82868475 , Also, are all of the images RGB? Mixing profiles for CMYK images means there will be some CMYK-to-CMYK conversions at output, which is never ideal and can cause problems. All RGB images will eventually get converted into the final print space, so as long as they include an embedded profile, the conversion will be color managed.

If you are color correcting the TIFFs, there is a strong argument for converting all of the RGB images into a single large gamut RGB editing space before making the edits. The problem with mixing small gamut display spaces like sRGB or even Display P3 is they "clip" a significant portion of the typical CMYK output space—a large portion of the CMYK blue/green spectrum can be outside of a small RGB space’s gamut. If you are editing in a space like sRGB, you can’t get at a saturated color like 100% cyan. In any case it is important to embed the RGB profile—images with no embedded profile will be listed as DocumentRGB in InDesign’s Link Info panel.

No, they don't all have to be the same.

But I like to do so, and set up a Color Management Method colorspace that already matches the embedded colorspace profile of pix that come through Photoshop. I make it a workflow habit to edit and save all images in Photoshop so that they have the same colorspace icc profile embedded within them.

I also make that same icc color profile choice for color management in InDesign. Keeping the workflow in the same colorspace through to next to last step cuts down on translations. The one big translation happens when exporting to PDF for prepress.