Monitor calibration and Lightroom issues

Need some help here. I calibrated my monitor today using the Colormunki photo and now when I start Lightroom all of my photo's look like they are either way overexposed or a negative. If I change the monitor profile back everything looks just fine. I'm using Lightroom 2015.9 and camera raw 9.9 with windows 10 pro.
Any help would be appreciated as I only have the Colormunki for a few more days.
Thanks,
Phil Curtis
