Topaz plugins not showing image

I have recently started to use a Mac Studio (Apple M1 Ultra chip, Ventura 13.1 operating systems). My raw photos are stored on a Drobo, and are processed mostly using Lightroom Classic (version 12) and Photoshop to a lesser degree.

I met with mixed success when I installed plugins into my new device: ON1 worked immediately, DxO after some effort. But two other apps, Luminar 4 and the Topaz products, fail in the same way when I try to use them as plugins. Both apps work well when I use them as standalone. But I cannot open the file as plugins.

Here I will refer to Topaz Sharpen AI as a specific example. When I attempt to open the file, and select "Edit with Lightroom adjustments", Sharpen AI returns with a error message "Unknown error/ could not open image. Please contact support with the image attached if the issue continues". Naturally, the issue continues(!) and I contact Topaz support. When I click the OK prompt, Topaz returns to me a tif file which is identical in appearance to the raw ("arw") file that went in.

I have just finished a long zoom call with Topaz support and there was no resolution, other than this: If I click "Edit original file" rather than "Edit with Lightroom adjustments", the image does open up normally and I can edit. Which I don't want to do since I want to leave sharpening to the end of my editing process. I have similar issue when trying to use Luminar 4: The image does not open up. Their the stand-alone application works once I place the raw file there.

I doubt that this is an issue with the Drobo/Mac interface. Rather, the issue seems to be in the interface of Lightroom and these apps, because two other apps ( DxO and ON1) work perfectly after pulling the raw images from the SAME Drobo as the Topaz apps.

I use Topaz products quite intensively but now I can't use them.
What's going wrong?