Adobe Premiere Pro (2022) Started Going Extremely Slow Over Night

This just started happening to me last week (mid June 2022).  I'm on a PC.  The menus often don't load - just blank white.  Autosave sometimes hangs the computer.  And it literally takes 3-4 seconds to select something!  I've got a deadline.  I don't know what to do.  I went back 2 updates.  

Something has gone really wrong with one of the latest updates. Didn't have any problem editing 4K 120fps before and suddenly I can't even preview the clips any more and trying to apply warp stabilizer to a few second nested clip will take up to 10 minutes. Reverted back to 22.0 and it works fine. Really looking for a solution to this, eager to use all the new features.

Just updated Premiere and everything is laggin for me as well. I had zero issues before the update. I have tried Cache, resetting, using high quality playback etc. Nothing helps.

same here. 2019 macbook pro maxed out in every respect (64gb ram,

AMD Radeon Pro 5500M 8 GB, 2.4 GHz 8-Core Intel Core i9)

It was absolutely fine on pp 2020 - didn't even need to proxy most of the time, even with 4k 10 bit footage. Now its as sluggish as anything even when I proxy. The timeline is ok if you scroll over it or press play (especially when proxied). However the problem is if you do a series of quick cuts, the whole system gets very sluggish & it's horrible to work with. I can see that it chews up my memory, and at it's worst will cause my computer to flash up a 'you've run out of memory' message. 

Rendering seems to be a bit quicker, but it prefer a system which performed faster and rendered slower. Always happy to take a tea break. 

I use after effects a great deal as well & the performance on this is greatly improved compared to old AE versions. In summary new premiere is absolutely terrible, after effects is pretty good. 

upgraded to the latest version of Monteray as I thought this might be the problem. It's not.

What are the hard drives (how many, what kind, what is on each, what capacity, and how full)?

Thank god someone has finally described exactly what I've been experiencing! The lag happened out of nowhere and Premiere Pro has been basically unusable since, can't drag anything, add effects or graphics, adjust clip size/position, etc.. I talked to customer care today and none of their tips on fixing it worked. Might've happened to us at the same time because it was working fine until maybe late January/early February. Like the other commenter said it could be a glitch with the latest MacOS maybe..

Did you happen to update to MacOS 12.2 or 12.2.1 recently? Premiere is running awful on latest MacOS. Stay on MacOS 12.1 until Adobe fixes it.

Are your other apps running fine? You might want to go through Adobe help and see if you can have a tech evaluate your computer to see if there's some gunk in the settings.