Overwriting old keyframes

[Doss310778945k64]

 I have to scroll down all the way to opacity, then select and delete the mask to replace them with new keyframes. Is there a faster way of going around this?

Also, how do I close every other effects except opacity?

[RobShultz]

There are no shortcuts for what you're asking about in Premiere. You may want to consider doing these tasks in After Effects if those shortcuts are important to you.