Basically the title, I was painting along, happy as can be until suddenly the lag attacked. It takes anywhere form 3-20 minutes to compute a single stroke of the paintbrush.
I've uninstalled and reinstalled on my fast SSD.
I've updated my windows preferences to both Best Performance on Power Settings and Best Performance on Substance Painter specifically.
I have "Saved and Reduced File Size"
I have upped my cache limit to the max and also moved all caches, preview, and temp files to my SSD.
I have tried only working on one layer at a time.
I have reduced the resolution of my UVs to 1k for the main body texture and 512 and 256 for the eyes. I have Sparse Vrtual Texture enabled/Hardware support acceleration.
I don't feel like my model is particularly super detailed or layered compared to other Subtance projects I see.
Processor: AMD Ryzen 5 2600 Six-Core ~3.4Ghz
Memory: 64GM DDR4
DirectX 12
When running performance tests while it was trying to compute a brush stroke it was using 66% of my GPU and somewhere around 35% of my main CPU.