From what I can tell, BobbyH5280 is talking about aligning to a key object. You can shift-select any number of objects (including the object you plan to make the Key Object), when you're finished selecting, then simply click the Key Object (do NOT hold shift.) You will then see the border around the Key Object appear, and can align as such. I use this feature about...a billion times a day. When you master this, you'll be golden. Also very helpful is object vertical or horizontal distribution based on a key object. For example, let's say you have 10 squares you want to distribute evenly by 10 px (or 10pts or 10 inches....whatever you want). You select all the squares, then click the key object (typically the object on either end (or top or bottom depending on whether you're distributing horizontally or vertically), then, in the Align panel, you'll see "Distribute Spacing", and here you can adjust the distribution size, and then click either Vertical Distribute or Horizontal Distribute, and voila, they will distribute perfectly. juliem18359647‌ I hope this helps, I assure you, you can accomplish what you need with Illustrator when you master alignment and distribution.
... View more