Automatic Image Compilation

Thanks for the responses. 

I have actively tried to solve this as well and I have come up with a pretty darn good solution so far...I have pulled a bunch of different ideas from others and created some custom scripting too.  This is a PoC to show that it can be done for 1 image.  I just need to clean it up and then figure out to it to run as a batch.  Be nice as this is my first attempt at PhotoShop Scripting

layerPixels2Selection = function(fLayer){
          if(mainPhoto.activeLayer.isBackgroundLayer){
             return;// background doesn't have a transparency mask
             }
          var desc = new ActionDescriptor();
          var ref = new ActionReference();
          ref.putProperty( charIDToTypeID( "Chnl" ), charIDToTypeID( "fsel" ) );
          desc.putReference( charIDToTypeID( "null" ), ref );
          var ref1 = new ActionReference();
          ref1.putEnumerated( charIDToTypeID( "Chnl" ), charIDToTypeID( "Chnl" ), charIDToTypeID( "Trsp" ) );
          desc.putReference( charIDToTypeID( "T   " ), ref1 );
          executeAction( charIDToTypeID( "setd" ), desc, DialogModes.NO );
  
}
function MoveLayerTo(fLayer,fX,fY) {
  var Position = fLayer.bounds;
  Position[0] = fX - Position[0];
  Position[1] = fY - Position[1];
  fLayer.translate(-Position[0],-Position[1]);
}
//demo
// Save the current preferences
var startRulerUnits = app.preferences.rulerUnits
var startTypeUnits = app.preferences.typeUnits
var startDisplayDialogs = app.displayDialogs
// Set Adobe Photoshop CS6 to use pixels and display no dialogs
app.preferences.rulerUnits = Units.PIXELS
app.preferences.typeUnits = TypeUnits.PIXELS
app.displayDialogs = DialogModes.NO
var mainPhoto = app.activeDocument;
layerPixels2Selection(mainPhoto)
mainPhoto.selection.invert();
var mainPhotoWidth = mainPhoto.width;
var mainPhotoHeight = mainPhoto.height;
var mainPhotoResolution = mainPhoto.resolution;
var mainPhotoAspect = mainPhoto.width / mainPhoto.height;
var selectionTopLeftXOffset = mainPhoto.selection.bounds[0].as('px')
var selectionTopLeftYOffset = mainPhoto.selection.bounds[1].as('px')
var selectionBottomRightXOffset = mainPhoto.selection.bounds[2].as('px')
var selectionBottomRightYOffset = mainPhoto.selection.bounds[3].as('px')
var selectionWidth = mainPhoto.selection.bounds[2].as('px') -  mainPhoto.selection.bounds[0].as('px');
var selectionHeight = mainPhoto.selection.bounds[3].as('px') -  mainPhoto.selection.bounds[1].as('px');
var selectionAspect = selectionWidth / selectionHeight;
//alert (selectionWidth + ", " + selectionHeight);
var lifestylePhoto = File("C:/Greeting Cards - Resized/lifestyle.jpg")
open (lifestylePhoto)
var lifestylePhoto = app.documents.getByName("lifestyle.jpg")
var lifestylePhotoAspect = lifestylePhoto.width / lifestylePhoto.height;
if (selectionAspect > lifestylePhotoAspect) {
          var lifestylePhotoNewWidth = selectionWidth; 
          var lifestylePhotoNewHeight = selectionWidth / lifestylePhotoAspect;
} else {
          var lifestylePhotoNewWidth = selectionHeight * lifestylePhotoAspect;
          var lifestylePhotoNewHeight = selectionHeight;
}
lifestylePhoto.resizeImage(lifestylePhotoNewWidth, lifestylePhotoNewHeight);
lifestylePhoto.selection.selectAll();
lifestylePhoto.selection.copy();
app.documents.add(mainPhotoWidth, mainPhotoHeight, mainPhotoResolution, 'newImage');
var newPhoto = app.documents.getByName("newImage");
newPhoto.paste();
MoveLayerTo(newPhoto.artLayers[0], selectionTopLeftXOffset, selectionTopLeftYOffset);
app.activeDocument = mainPhoto;
mainPhoto.selection.selectAll();
mainPhoto.selection.copy();
app.activeDocument = newPhoto
newPhoto.paste();
// Reset the application preferences
app.preferences.rulerUnits = startRulerUnits
app.preferences.typeUnits = startTypeUnits
app.displayDialogs = startDisplayDialogs