"A running instance of Acrobat has caused an error" - RDS Server Environment

@warm_twinkle To address this elusive issue, you'll need to focus on ensuring Acrobat has the most stable and isolated environment possible within RDS, along with proactive resource management. Firstly, double-check that your RDS servers are consistently updated with the latest Windows Server patches, as these often contain fixes for session management and resource handling that can impact applications. Next, critically examine the folder permissions and exclusions for Adobe's application data and temporary files (e.g., C:\Users\username\AppData\Local\Temp\Acrobat and C:\ProgramData\Adobe\Acrobat). Ensure that users have full write access to these temporary locations, and consider adding these paths to the antivirus/security software exclusion lists on your RDS servers. Aggressive scanning of these frequently accessed temporary files can often cause file locks and lead to these "instance" errors. Furthermore, implement scheduled tasks to periodically clear temporary Adobe files and orphaned processes (e.g., specific Acrobat.exe or AcroCEF.exe processes that remain active after user logoff or crashes) during off-peak hours. Finally, explore Adobe's official documentation for Acrobat deployments in virtualized environments or Citrix/RDS setups, as they often provide specific best practices or registry keys not commonly found in general community forums that can optimize performance and stability in such complex shared environments.

Please be very cautious, if anyone reaches out to you directly via email or private message offering help, it's unfortunately far more likely to be a scammer than an official Adobe representative. Adobe's support typically happens through their official channels, not unsolicited direct messages. If you're unable to follow the steps described, you'll need to await help from an adobe employee for the next step.  (if you don't get a reply here from a badged employee within 24 hours, repost.)