Adobe Illustrator mouse cursor Flickering.

I may be able to help. I have fixed my PC and Mac - it has to do with the Wacom drivers installed.
What OS are you using?

I am able to resolve flickering issue, the steps are mentioned here in this video link posted on Youtube: [SOLVED] Flickering Cursor issue in Illustrator CC 2015, 2017 How to - YouTube

After weeks, and I mean weeks, of troubleshooting and research, I have come up with a temporary solution to an annoying issue: that being the mouse cursor flickering and disappearing while using Illustrator CC on a Wacom Cintiq and iMac.

Before I get into it, here are my specs:

iMac 21.5 inch Retina 4K Display running El Capitan (Don't even bother with OS Sierra)

Wacom Cintiq 22HD Touch

Adobe CC Illustrator 2017 (and 2015)

Issue:

While working in Illustrator and using a Wacom Cintiq pen, (regardless if on selection tool, brush, etc) the cursor flickers and disappears, and also slows down performance and also make's it sometimes unable to use Tools on canvas and in interface area.

Temporary Solution:

Here is the work around. Open Illustrator CC 2017. Keep it open, then restart your Mac. When you log back into your OS, you'll notice there is an arrow under the Illustrator icon in your Dock. Open Illustrator, it will start-up, and will work fine. The problem will come back if you close Illustrator, and then re-open it again. So make sure you always keep it open, even when putting your computer to sleep. If you need to close Illustrator for whatever reason, do so, re-start the program, leave it on, and then restart your computer. Wacom drivers also seem to be irrelevant to this issue, as I ended up completely uninstalling all Wacom drivers as the Cintiq is still running fine without it (pressure points working, cursor lined up to mouse, etc)