I'll add my other two cents what improved my experience hugely in Adobe Bridge in conjunction with ACR:
Go to the NVIDIA-Control-Panel (right klick on your Desktop), then
--> 3D-Settings
--> Manage 3D-Settings
--> Either under the Global-tab or set it up specifically for Adobe Bridge
--> Cuda - Sysmem Fallback Policy: Change this to Prefer Sysmem Fallback
As far as my understanding goes, ACR / Bridge won't touch the system RAM in certain circumstances and for certain calculations. This setting allows your graphics card to off-load files stored in VRAM to go to RAM. It will be somewhat slower in some cases, but at least my PC now keeps on functioning even with VRAM filled to the brim.
Still, RAM will keep on climbing over time and force a restart of Bridge eventually.