I updated to Photochop CC 2018 yesterday and "I got Adobe Photoshop CC 2018 cannot be opened because of a problem"

I had this issue, and I found a fix:

Configuration error in Adobe Creative Cloud

Even though I was getting the "Adobe Photoshop CC 2018 cannot be opened because of a problem" error, and not an "Error: 16" message, changing the permissions on the SLStore and Adobe PCD folders (as detailed in the link) fixed the problem!

NOT ANSWERED

I have the same issue.  Photoshop is the only app not opening.  Illustrator, indesign open just fine.  I also get a problem report dump as --pk- posted.  I have fully uninstalled, rebooted, cleared things, reinstalled, same issue.  I have tried many combinations of uninstall and reinstalling to try and figure this out.  Nothing has worked yet.  DOA

I'm having the same exact problem. Uninstalling/reinstalling did not help. It's just photoshop, the other apps work fine.

Process:               Adobe Photoshop CC 2018 [15210]

Path:                  /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/MacOS/Adobe Photoshop CC 2018

Identifier:            com.adobe.Photoshop

Version:               19.0.1 (19.0.1.334)

Code Type:             X86-64 (Native)

Parent Process:        ??? [1]

Responsible:           Adobe Photoshop CC 2018 [15210]

User ID:               1591189349

Date/Time:             2017-11-15 10:58:37.487 -0800

OS Version:            Mac OS X 10.13.1 (17B48)

Report Version:        12

Bridge OS Version:     3.0 (14Y661)

Anonymous UUID:        44F3B0EF-0E41-9E51-FC16-81ACA9ED5A0A

Sleep/Wake UUID:       903D79CD-76C5-4FC8-82DF-4C4FD848147B

Time Awake Since Boot: 8300 seconds

Time Since Wake:       790 seconds

System Integrity Protection: enabled

Crashed Thread:        0

Exception Type:        EXC_CRASH (SIGABRT)

Exception Codes:       0x0000000000000000, 0x0000000000000000

Exception Note:        EXC_CORPSE_NOTIFY

Termination Reason:    DYLD, [0x1] Library missing

Application Specific Information:

dyld: launch, loading dependent libraries

Dyld Error Message:

  Library not loaded: @executable_path/../Frameworks/AdobeCrashReporter.framework/Versions/A/AdobeCrashReporter

  Referenced from: /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/MacOS/Adobe Photoshop CC 2018

  Reason: no suitable image found.  Did find:

  /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/MacOS/../Frameworks/AdobeCrashReporter.framework/Versions/A/AdobeCrashReporter: open() failed with errno=13

  /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/MacOS/../Frameworks/AdobeCrashReporter.framework/Versions/A/AdobeCrashReporter: stat() failed with errno=1

  /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/MacOS/../Frameworks/AdobeCrashReporter.framework/Versions/A/AdobeCrashReporter: open() failed with errno=13

  /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/MacOS/../Frameworks/AdobeCrashReporter.framework/Versions/A/AdobeCrashReporter: stat() failed with errno=13

Binary Images:

       0x10c7f9000 -        0x1132e3f37 +com.adobe.Photoshop (19.0.1 - 19.0.1.334) <121F32F6-AC5E-3943-80D3-FC9D60FCC1FB> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/MacOS/Adobe Photoshop CC 2018

       0x1141e5000 -        0x11421ffef +libtbb.dylib (0) <10144FAB-48B9-34ED-833B-A3F7E65BC4ED> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/libtbb.dylib

       0x114262000 -        0x11430bfff +com.adobe.AdobeExtendScript (ExtendScript 4.5.7 - 4.5.7.1) <82B65CE1-CF24-37A2-9D2D-EEA6AF1158B7> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeExtendScript.framework/Versions/A/AdobeExtendScript

       0x11436d000 -        0x114408fff +com.adobe.AdobeScCore (ScCore 4.5.7 - 4.5.7.1) <06E4B531-583D-37DA-A64E-D7C2E72C017B> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeScCore.framework/Versions/A/AdobeScCore

       0x11445a000 -        0x11460aff7 +com.adobe.aif (Adobe Image Foundation Library 6.0.00.1 - 6.0.00.1) <41E935C7-96D1-3060-AB6D-D545921BE10F> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/aif.framework/Versions/A/aif

       0x114760000 -        0x1147cdff7 +com.adobe.manta (Adobe Manta Library 2.0.00.1 - 2.0.00.1) <D8CBEC7C-A1D1-3469-BF40-096FDA9F0BCE> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/manta.framework/Versions/A/manta

       0x11485b000 -        0x114873ff7 +CITThreading (???) <13AE79F2-B3B5-3B8C-9054-9D2B73401C88> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/CITThreading.framework/Versions/A/CITThreading

       0x1148b6000 -        0x1149b4ff3 +ZXPSignLib-minimal-dylib.dylib (0) <B50C7884-6179-3925-AF15-0013257D0F6B> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/ZXPSignLib-minimal-dylib.dylib

       0x1149e2000 -        0x114b47ff7 +com.adobe.AdobeXMPFiles (Adobe XMP Files 5.7 -f 26 - 79.160451) <D9D1C497-7EFF-3AF2-A42D-E51721FE1483> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeXMPFiles.framework/Versions/A/AdobeXMPFiles

       0x114c75000 -        0x114d82fff +com.adobe.amtlib (10.0.0.221 - 10.0.0.221) <2DB81FF7-87C4-3307-A45E-96FCF6FD8AB1> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/amtlib.framework/Versions/A/amtlib

       0x114d98000 -        0x115073fef +com.adobe.PlugPlugOwl (8.0.0.55 - 8.0.0.55) <B858CAC6-FC69-36E2-BEFB-18AE865CD8BA> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/PlugPlugOwl.framework/Versions/A/PlugPlugOwl

       0x1152bd000 -        0x115333fff +com.adobe.AdobeSVGAGM (1.0.0 - 1.0.0.38473) <D40C91AF-CDB4-3081-A073-05422FD02074> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeSVGAGM.framework/Versions/A/AdobeSVGAGM

       0x11541c000 -        0x1154c5ff7 +com.adobe.ICUConverter (4.0 - 3.61) <E20E390A-9BAF-3454-BA16-7B9CCD4CA8F0> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/ICUConverter.framework/Versions/4.0/ICUConverter

       0x1154f5000 -        0x11553dff7 +com.adobe.ahclientframework (3.0.0.6 - 3.0.0.6) <088B16D4-24A8-3F73-89D8-45CFA76C5D8D> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/ahclient.framework/Versions/A/ahclient

       0x11557b000 -        0x1156f5ff7 +com.adobe.AdobeXMPCore (Adobe XMP Core 5.6 -c 140 - 79.160451) <BA9FA2D4-A630-31C2-991E-463A1637F95A> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeXMP.framework/Versions/A/AdobeXMP

       0x11584b000 -        0x1159ecfff +com.adobe.owl (AdobeOwl version 5.2.11 - 5.2.11) <75F67E64-09C9-3AA2-AC98-8B1C341615DD> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeOwl.framework/Versions/A/AdobeOwl

       0x115a3b000 -        0x115da2ffb +com.adobe.MPS (AdobeMPS 5.8.1.38423 - 5.8.1.38423) <E3C57181-5402-3F70-95D3-849252D8CC45> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeMPS.framework/Versions/A/AdobeMPS

       0x115e16000 -        0x115e3afff +VulcanControl.dylib (5.3.0.16 - 5.3.0.16 Copyright 2016, Adobe Systems Incorporated. All rights reserved.) <32AA6861-E0A7-37F8-8CE9-FCE97E3BFD07> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/VulcanControl.dylib

       0x115e68000 -        0x116138fff +com.adobe.AGM (AdobeAGM 4.30.87.39233 - 4.30.87.39233) <5C37D655-2717-3391-9067-BC869E081583> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeAGM.framework/Versions/A/AdobeAGM

       0x1161a6000 -        0x11649bfff +com.adobe.CoolType (AdobeCoolType 5.17.00.39233 - 5.17.00.39233) <77E067B6-43F5-3504-BD43-E97B6DBB92B6> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeCoolType.framework/Versions/A/AdobeCoolType

       0x1164e8000 -        0x116508ff7 +com.adobe.BIBUtils (AdobeBIBUtils 1.1.39233 - 1.1.39233) <EBB9A3A4-61EA-359B-9AE6-9A53B212ED9D> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeBIBUtils.framework/Versions/A/AdobeBIBUtils

       0x116511000 -        0x116535ff7 +com.adobe.AXE8SharedExpat (AdobeAXE8SharedExpat 3.8.0.34320 - 3.8.0.34320) <674F1792-D790-3E12-8C0F-85CAF9D848B1> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeAXE8SharedExpat.framework/Versions/A/AdobeAXE8SharedExpat

       0x116559000 -        0x116683ff7 +com.winsoft.wrservices (WRServices 12.1.0 - 12.1.0) <75B95734-75E4-3E7E-B8E3-DB51C053E4DC> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/WRServices.framework/Versions/A/WRServices

       0x1166db000 -        0x1167dbfff +com.adobe.ACE (AdobeACE 2.20.02.39233 - 2.20.02.39233) <CBA6EA4D-D7C8-3334-9B26-01D915AD4D5F> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeACE.framework/Versions/A/AdobeACE

       0x1167f8000 -        0x116811ff7 +com.adobe.BIB (AdobeBIB 1.2.03.39233 - 1.2.03.39233) <B7C38DBC-0159-374B-8ADF-1936BA40AA63> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeBIB.framework/Versions/A/AdobeBIB

       0x11681b000 -        0x1168dbff7 +com.adobe.JP2K (1.2.2 - 1.2.2.38423) <F1382526-0DDF-39D3-88BA-BDA205012453> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobeJP2K.framework/Versions/A/AdobeJP2K

       0x116925000 -        0x116e7dfef +com.nvidia.cg (2.2.0006 - 0) /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/Cg.framework/Cg

       0x1174eb000 -        0x117685fff +com.adobe.headlights.LogSessionFramework (7.4.1.60.45263) <2116CCCF-BA38-366C-8BCE-91827BA52E6D> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/LogSession.framework/Versions/A/LogSession

       0x11775b000 -        0x1184a0fff +com.adobe.ICUData (4.0 - 3.61) <B9864D01-126E-3C56-B04C-993F9890F6AD> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/ICUData.framework/Versions/4.0/ICUData

       0x1184ba000 -        0x1184e3ff7 +com.adobe.PDFSettings (AdobePDFSettings 1.04.0 - 1.4) <E07D101E-E47A-392A-8A44-005B49393DEC> /Applications/Adobe Photoshop CC 2018/Adobe Photoshop CC 2018.app/Contents/Frameworks/AdobePDFSettings.framework/Versions/A/AdobePDFSettings

       0x11b24d000 -        0x11b29798f  dyld (519.2.1) <CD85EFBA-B9D6-3FD5-B777-A23B2DDEF192> /usr/lib/dyld

    0x7fff24097000 -     0x7fff2409bffb  com.apple.agl (3.3.1 - AGL-3.3.1) <E5579A48-761F-3763-B924-2D1511935787> /System/Library/Frameworks/AGL.framework/Versions/A/AGL

    0x7fff25471000 -     0x7fff262ccff7  com.apple.AppKit (6.9 - 1561.10.101) <AC5C259A-615C-3929-8586-0BC920696AFA> /System/Library/Frameworks/AppKit.framework/Versions/C/AppKit

    0x7fff27181000 -     0x7fff27181fff  com.apple.Carbon (158 - 158) <C34E5FF0-4FDA-35F1-85C2-FDAC4EDE8331> /System/Library/Frameworks/Carbon.framework/Versions/A/Carbon

    0x7fff27e11000 -     0x7fff282b0fef  com.apple.CoreFoundation (6.9 - 1445.12) <C01736CF-D425-316C-A984-C8AF46EAD8CD> /System/Library/Frameworks/CoreFoundation.framework/Versions/A/CoreFoundation

    0x7fff28f52000 -     0x7fff28f52fff  com.apple.CoreServices (822.9 - 822.9) <F56B0D43-BD84-3214-AB01-346BD33C9583> /System/Library/Frameworks/CoreServices.framework/Versions/A/CoreServices

    0x7fff29f25000 -     0x7fff2a2e8fff  com.apple.Foundation (6.9 - 1443.14) <70D20A4F-74BC-34D6-8451-DF943C5AA42F> /System/Library/Frameworks/Foundation.framework/Versions/C/Foundation

    0x7fff2a5fc000 -     0x7fff2a697fff  com.apple.framework.IOKit (2.0.2 - 1445.20.1) <3316799C-14BC-366E-8A58-67485E5CD69E> /System/Library/Frameworks/IOKit.framework/Versions/A/IOKit

    0x7fff30389000 -     0x7fff303d6ffb  com.apple.opencl (2.8.11 - 2.8.11) <5C8205DF-43F1-3189-93DE-2E340C9A53B8> /System/Library/Frameworks/OpenCL.framework/Versions/A/OpenCL

    0x7fff320fe000 -     0x7fff3210cffb  com.apple.opengl (16.2.1 - 16.2.1) <66266ABC-2655-337C-AC64-955A16A8FCBB> /System/Library/Frameworks/OpenGL.framework/Versions/A/OpenGL

    0x7fff32f60000 -     0x7fff331a3fff  com.apple.QuartzCore (1.11 - 574.10.7) <556DE20F-0F03-31C9-B5EC-CDE82D8879BA> /System/Library/Frameworks/QuartzCore.framework/Versions/A/QuartzCore

    0x7fff339d8000 -     0x7fff33cf3ff7  com.apple.security (7.0 - 58286.20.16) <ED7F62C8-4E61-34E0-9F1B-59DE4B8BD334> /System/Library/Frameworks/Security.framework/Versions/A/Security

    0x7fff341c4000 -     0x7fff341c9fff  org.twain.dsm (1.9.5 - 1.9.5) <C53A4DA0-7BD1-34DD-A2FA-BC0E38E536EB> /System/Library/Frameworks/TWAIN.framework/Versions/A/TWAIN

    0x7fff4dce4000 -     0x7fff4dd3aff3  libcups.2.dylib (462.1) <4F4F85FD-D907-3D51-A3F0-2A239E165A07> /usr/lib/libcups.2.dylib

    0x7fff4ed9d000 -     0x7fff4ef32fef  libsqlite3.dylib (274.1) <075468C1-75CE-318F-9E9B-F62B6A88E1B3> /usr/lib/libsqlite3.dylib

I've been receiving the same error for Photoshop, Illustrator and InDesign CC 2018. Uninstalling, reinstalling and restarting my computer multiple times have not resolved the issue.