Is youtube 1080p full hd better quality than high quality 1080p hd when using adobe premiere pro?

[Jay Rule]

I upload videos to Youtube often so I would like to know which setting will offer the best resolution and frame rate. 

[MarekMularczyk]

Both options you mentioned give you the same resolution (1080p) so doesn;t matter.

As for frame rate, this depends on the frame rate of your sequence.

[Jay Rule]

But which is better quality 1080P? Is it even noticeable?

[R Neil Haugen]

They're the same. 1080 is 1080. And I think those are both using long-GOP interframe codecs.

Check the bit rates between them, see if there's a difference there. Higher bitrates have typically more fine details.

For intraframe codecs like ProRes, the DNx variants, or Cineform, you select Q by which form of that codec you select.

[Warren Heaton]

High Quality 1080p HD is one pass variable bit rate with a target bit rate of 20 Mbps using Hardware encoding if available.

YouTube 1080p Full HD is one pass variable bit rate with a target bit rate of 16 Mbps using Hardware encoding if available. 

Image quality should be about the same; however, the file created via YouTube 1080p Full HD should be about 80% smaller resulting in a faster upload.

You can queue both at the same time in Adobe Media Encoder by using the Add Output button, compare the results, and upload whichever one you prefer.