low level exception in adobe player (player:63)

After a long multiclip edit I finally could export but than started the trouble with crashes by low level exception in adobe player (player:63). I couldn't fix it and had to export did different kind of recommendations from youtube and internet but had to go back to premiere 2020 and woth fimalcut XML import the sequence. This took me a lot of time so what happened. I edited multiclip with different codecs MXF and MP4/MOV H.264 10 bit 4:2:2. Anybody an idea what went wrong and how to solve this in 2021.

kind regards Calixte

system: