P: (Windows) Photoshop v27.9.1 Crashes at launch: OpenCLOn12.dll exception 0xc0000409 (possible Windows/NVIDIA driver conflict)

I had a very similar issue with Photoshop not opening, and it’s frustrating when reinstalling doesn’t fix it. Since Lightroom and the Beta version are working, it sounds like something specific to the main Photoshop installation or its settings. I’d also try resetting Photoshop preferences and checking whether any recent Creative Cloud or Windows update caused the issue. Hopefully you can get it running again without another reinstall.

As a follow up to the original post, uninstalled and reinstalled using the “Cloud Cleaner” tool.  Photoshop would opened once.  I could open and edit an image but when I attempted to open the program again, same failure...splash screen, blue screen then nothing.  I saw this same behavior characterized in another question herein.  Obviously, something weird going on in Photoshop.  Do not see how anything in the OS could change from closing and reopening a program.  Need insights into how to determine what is happening.

Not certain how much detail can be provided for software that does not start.  Running the latest version of Photoshop, Creative Cloud states that it is 27.9.1.  When attempting to start Photoshop the “splash” screen comes up and a little blue will spins for a second or two.  Then everything disappears and the program does not start.  Nothing on the system changed to my knowledge.  Of course, one can never say for sure since it seems Adobe and Microsoft are on the system more than I am.  That aside, I just went to start the program and it would not run.

Curious is Lightroom classic runs as will Adobe Photoshop beta (27.11).  It was installed two days ago.  Also noticed that under Recent updates Photoshop is missing from my list of apps.  Previously, I thought it was listed with the date of the last update.  Have tried pretty much every troubleshooting approach offered on Adobe or the internet.  Clearly, this is not an uncommon problem that Adobe refuses to do anything about.

System details are Windows 11 Pro build 26200.  i9-14900k @ 3200MHz.  128Gb Ram.  NVIDIA GeForce RTX 4060 Ti graphics.

Appreciate any ideas that might actually work.  Figuring if total reinstalls are what is required every six months out of a program need to find another program.  The Adobe approach to programming reminds me of Windows 98 days from back in the mid to late ‘90s in that one can count on have to do a total reconfiguration on a regular basis.

Did previous versions run OK?

What plugins do you use? Are the same plugins installed for both the release and Beta versions?

Try starting Photoshop while holding down the Shift key.  This forces Photoshop to open but ignores all installed plugins, extensions etc.

Open the Beta version and go Help > System Info > Copy and paste to this thread.  This will tell us what we are dealing with.  

When I load Photoshop, it locks up and does not respond to anything. it just freezes once it loads does not respond to keyboard or mouse, have to use Task Manager to close, I have all the newest updates the version is V27.91, I also have Photoshop Bata that works perfectly fine

Unfortunately you haven't given us detailed infos about the issue and any information about your system. Therefore, all proposed solutions are a look into the crystal ball.

Please decribe your issure more detailed. 

Do you try to open a new file or an existing file?

Do you get an error message or a crash report?  Please post the message word-by-word. Do you’ve send the crash report to Adobe?

Which operating system do you use?

If it possibel provide a copy of your 'System Info'. This can be get from the Photoshop menu item Help > System Info. There's a copy button in the System Info dialog. Press this button and paste the info into a text file and attach it to your next forum post.

Check if your system is up-to-date. Do you have installed all recent updates and patches for the operating system and the device drivers, especially the graphic driver? If you’ve buildin a Nvidia graphic card make also sure that you have installed the Studio version and not the Game Ready version of your NVidia driver.

Try first a reset of the Photoshop preferences: https://helpx.adobe.com/ie/photoshop/using/preferences.html#Manually

Remember to back up your settings before doing the preference reset:https://helpx.adobe.com/ie/photoshop/using/preset-migration.html

If this doesn’t help try a manually removing the preferences files. This is the most complete method for restoring to the default state. The manual method ensures all preferences which may be causing a problem and prevents Photoshop form loading.

Please follow the steps below:

1. Quit Photoshop.
2. Navigate to Photoshop's Preferences folder.
   MacOS: …Users/[user name]/Library/Preferences/Adobe Photoshop [version] Settings
   Windows: …Users/[user name]/AppData/Roaming/Adobe/Adobe Photoshop [version]/Adobe Photoshop [version] Settings
    
   Note: The User Library folder is hidden by default. To access the content in the hidden folders see here:
   MacOS: Access hidden macOS library files
   Windows: Show hidden files, folders, and filename extensions in Windows
    
3. Drag the entire Adobe Photoshop [Version] Settings folder to a safe place to a backup your settings
4. Open Photoshop.

 New preferences files with the default settings will be created automatically.

27. 9. 1 constantly crashing on opening any project file, last version was crashing on Camera raw, this time it's not even let me use it