The main relevant difference is that Responsive uses an iframe to contain the topic content, whereas Frameless does not use frames.
What this means is that for Responsive, the toc and header are separate files from the topic. Clicking on an entry in the toc only changes the content inside the frame, rather than the whole web page.
For Frameless, the toc, header and topic are a single file, so when you click on a link you are loading a whole new page. (It's not quite that simple, because javascript is involved, but it's close enough for our purposes.)
While this would suggest that Responsive is better because the toc doesn't have to reload, there are other benefits to using Frameless, including:
- better search engine optimisation (SEO) because frames aren't used.
- each topic has a unique URL, without requiring complicated coding additional coding
compare:
responsive: C:/temp/outputs/test-multiscreen-variables/Responsive_HTML/index.htm#t=First_Topic.htm
frameless: C:/temp/outputs/test-multiscreen-variables/Frameless/First_Topic.htm
- it's likely future development will concentrate on Frameless output
- more comprehensive built-in skin customisation options
There are probably other benefits but that's what I can think of off the top of my head.
Hope that helps explain things. Post back with any other questions you have.