Hi Studio57NL,
When you upgrade to the latest version of macOS or launch a Creative Cloud application for the first time on the latest versions of macOS, you may see a warning message that indicates Adobe software needs to be optimized for better performance.
This is due to some 32-bit components that we are working to address in a future Creative Cloud update.
Please note that no action is required from you at this time and your applications will still run as normal.
For more information, see 32-bit app compatibility with macOS High Sierra 10.13.4 and later - Apple Support.
Let us know if you have any more queries.