All Adobe products quit working

Adobe products worked...and then they didn't.  Photoshop suddenly appears not to be installed anymore.  There's still a Premiere icon, but Premiere doesn't open.  Possibly most problematically, Adobe Sign doesn't work.  It just has the little "loading" circle...forever.  Both on Adobe Sign and on the Creative Cloud installer.

This is a problem.  I pay for and use these products for work.  Coronavirus time is not a great time to suddenly not have the tools I need in order to work from home.  What's the deal?