Yes, you can turn off hyphenation so that the box is unchecked for every new text box.
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1. If you haven't already, in Preferences > General, uncheck Show Home Screen When No Documents Are Open. (You can turn this back on later if you use its features.)
2. With no documents open, use CMD+OPT+T to open the Paragraph panel. (Alternatively, find it in Window > Type & Tables > Paragraph, OR type "paragraph" in the Help menu search field to jump to that menu item.)
3. Uncheck the Hyphenate option.
Hyphenation is now off by default for all new text boxes and will "stick" when you close InDesign and restart.
Instructions applicable for InDesign 2023 and 2024.

