Is there a way to associate a keyboard shortcut for the "Hyphenate" option?

Hi @Roger Breton , If @pixxxelschubser ’s toggle option doesn’t work for you (toggling Hyphenation off leaves it turned of for new text creation), it can be scripted with the script assigned a key command. Something like this would turn off Hyphenation for the selected range of text :

var s = app.activeDocument.selection
if (app.activeDocument.selection.length == 0) {
	alert("No Text Selected")
} else{
    if (s[0].hasOwnProperty("paragraphs")) {
        s[0].paragraphs.everyItem().hyphenation = false
    }    
}

I think you've found the only control in the entire layout that has no key assignment.

There is an assignment for the hyphenation menu; open that and a shift-tab takes you to the checkbox. Might be able to script that, or use a system or keyboard macro.