Using the layout grid typesetting,How to accurately control the width of the 2 -column frame grad?

Layout grids don't seem to be available in my US English version, so I'm guessing they are a CJK feature. I don't see anything in the help files that says you can specify the number of cells in the grid, but I do notice in your file that the total number of cells in the tow columns is the same as the number of cells in the original one-column frame, so I expect that's where the "22" is coming from. I'm afraid I have no clue how you would change this for a two column frame, but I bet if you insted used two one column frames in that part of the layout your problem would disappear.

Those green box patterns originate on the Parent page. They could be edited there, but interestingly, I could not select them on the Parent page. I wonder if your document is corrupt?