Basically when I use Edit in Photoshop 2021 I get scaling issues like this - i.e. the mouse pointer appears in one place but affects the image in another.
So when I try and draw around the eye on the right the effect is as above.
If I export the image to the desktop and open manually in Photoshop this doesn't happen - only when exporting from Lightroon Classic.
Both Lightroom and Photoshop individually work fine on different monitors at different resolution, but like most people, I like to use the Edit in Photoshop function as it is a fundamental part of my workflow.
I thought to start with this was a Photoshop problem but now I am not sure.
I have tried uninstalling and reinstalling without plugins but nothing has changed. I've even tried reinstalling the OS.
You can read the full thread here under the Photoshop section.
https://community.adobe.com/t5/photoshop-ecosystem-discussions/scaling-issue-in-photoshop-2021-v22-5...
Many Thanks
Ian